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Three-dimensional breast cancer models mimic hallmarks of size-induced tumor progression

Tumor size is strongly correlated with breast cancer metastasis and patient survival. Increased tumor size contributes to hypoxic and metabolic gradients in the solid tumor and to an aggressive tumor phenotype. Thus, it is important to develop three-dimensional (3D) breast tumor models that recapitu...

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Detalles Bibliográficos
Publicado en:Cancer Res
Main Authors: Singh, Manjulata, Mukundan, Shilpaa, Jaramillo, Maria, Oesterreich, Steffi, Sant, Shilpa
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4947371/
https://ncbi.nlm.nih.gov/pubmed/27216179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-15-2304
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