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Identifying Molecular Signatures of Distinct Modes of Collective Migration in Response to the Microenvironment Using Three-Dimensional Breast Cancer Models

SIMPLE SUMMARY: The objective of this study was to investigate the role of two microenvironmental factors, namely, tumor-intrinsic hypoxia and secretome in inducing collective migration. We utilized three-dimensional (3D) discrete-sized microtumor models, which recapitulate hallmarks of transition o...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Ardila, Diana Catalina, Aggarwal, Vaishali, Singh, Manjulata, Chattopadhyay, Ansuman, Chaparala, Srilakshmi, Sant, Shilpa
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8004051/
https://ncbi.nlm.nih.gov/pubmed/33804802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13061429
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