An abundant class of non-coding DNA can prevent stochastic gene silencing in the C. elegans germline

Cells benefit from silencing foreign genetic elements but must simultaneously avoid inactivating endogenous genes. Although chromatin modifications and RNAs contribute to maintenance of silenced states, the establishment of silenced regions will inevitably reflect underlying DNA sequence and/or stru...

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Publicat a:Cell
Autors principals: Frøkjær-Jensen, Christian, Jain, Nimit, Hansen, Loren, Davis, M Wayne, Li, Yongbin, Zhao, Di, Rebora, Karine, Millet, Jonathan RM, Liu, Xiao, Kim, Stuart K, Dupuy, Denis, Jorgensen, Erik M, Fire, Andrew Z
Format: Artigo
Idioma:Inglês
Publicat: 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4947018/
https://ncbi.nlm.nih.gov/pubmed/27374334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.05.072
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