An abundant class of non-coding DNA can prevent stochastic gene silencing in the C. elegans germline

Cells benefit from silencing foreign genetic elements but must simultaneously avoid inactivating endogenous genes. Although chromatin modifications and RNAs contribute to maintenance of silenced states, the establishment of silenced regions will inevitably reflect underlying DNA sequence and/or stru...

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Bibliografische gegevens
Gepubliceerd in:Cell
Hoofdauteurs: Frøkjær-Jensen, Christian, Jain, Nimit, Hansen, Loren, Davis, M Wayne, Li, Yongbin, Zhao, Di, Rebora, Karine, Millet, Jonathan RM, Liu, Xiao, Kim, Stuart K, Dupuy, Denis, Jorgensen, Erik M, Fire, Andrew Z
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2016
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4947018/
https://ncbi.nlm.nih.gov/pubmed/27374334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.05.072
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