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Forces Driving Chaperone Action

It is still unclear what molecular forces drive chaperone-mediated protein folding. Here, we obtain a detailed mechanistic understanding of the forces that dictate the four key steps of chaperone-client interaction: initial binding, complex stabilization, folding, and release. Contrary to the common...

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Bibliografiske detaljer
Udgivet i:Cell
Main Authors: Koldewey, Philipp, Stull, Frederick, Horowitz, Scott, Martin, Raoul, Bardwell, James C. A.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4947014/
https://ncbi.nlm.nih.gov/pubmed/27293188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.05.054
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