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Structure-Function Analyses of a Staphylococcus epidermidis Autoinducing Peptide Reveals Motifs Critical for AgrC-type Receptor Modulation

Staphylococcus epidermidis is frequently implicated in human infections associated with indwelling medical devices due to its ubiquity in the skin flora and formation of robust biofilms. The accessory gene regulator (agr) quorum sensing (QS) system plays a prominent role in the establishment of biof...

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Bibliographic Details
Published in:ACS Chem Biol
Main Authors: Yang, Tian, Tal-Gan, Yftah, Paharik, Alexandra E., Horswill, Alexander R., Blackwell, Helen E.
Format: Artigo
Language:Inglês
Published: 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4946969/
https://ncbi.nlm.nih.gov/pubmed/27159024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.6b00120
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