CELF RNA binding proteins promote axon regeneration in C. elegans and mammals through alternative splicing of Syntaxins

Axon injury triggers dramatic changes in gene expression. While transcriptional regulation of injury-induced gene expression is widely studied, less is known about the roles of RNA binding proteins (RBPs) in post-transcriptional regulation during axon regeneration. In C. elegans the CELF (CUGBP and...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Chen, Lizhen, Liu, Zhijie, Zhou, Bing, Wei, Chaoliang, Zhou, Yu, Rosenfeld, Michael G, Fu, Xiang-Dong, Chisholm, Andrew D, Jin, Yishi
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2016
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4946901/
https://ncbi.nlm.nih.gov/pubmed/27253061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.16072
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