Mapping replication dynamics in Trypanosoma brucei reveals a link with telomere transcription and antigenic variation

Survival of Trypanosoma brucei depends upon switches in its protective Variant Surface Glycoprotein (VSG) coat by antigenic variation. VSG switching occurs by frequent homologous recombination, which is thought to require locus-specific initiation. Here, we show that a RecQ helicase, RECQ2, acts to...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Devlin, Rebecca, Marques, Catarina A, Paape, Daniel, Prorocic, Marko, Zurita-Leal, Andrea C, Campbell, Samantha J, Lapsley, Craig, Dickens, Nicholas, McCulloch, Richard
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2016
Assuntos:
Genes and Chromosomes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4946898/
https://ncbi.nlm.nih.gov/pubmed/27228154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.12765
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