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Mapping replication dynamics in Trypanosoma brucei reveals a link with telomere transcription and antigenic variation
Survival of Trypanosoma brucei depends upon switches in its protective Variant Surface Glycoprotein (VSG) coat by antigenic variation. VSG switching occurs by frequent homologous recombination, which is thought to require locus-specific initiation. Here, we show that a RecQ helicase, RECQ2, acts to...
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| Publié dans: | eLife |
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| Auteurs principaux: | , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
eLife Sciences Publications, Ltd
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4946898/ https://ncbi.nlm.nih.gov/pubmed/27228154 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.12765 |
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