Mapping replication dynamics in Trypanosoma brucei reveals a link with telomere transcription and antigenic variation

Survival of Trypanosoma brucei depends upon switches in its protective Variant Surface Glycoprotein (VSG) coat by antigenic variation. VSG switching occurs by frequent homologous recombination, which is thought to require locus-specific initiation. Here, we show that a RecQ helicase, RECQ2, acts to...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:eLife
Egile Nagusiak: Devlin, Rebecca, Marques, Catarina A, Paape, Daniel, Prorocic, Marko, Zurita-Leal, Andrea C, Campbell, Samantha J, Lapsley, Craig, Dickens, Nicholas, McCulloch, Richard
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: eLife Sciences Publications, Ltd 2016
Gaiak:
Genes and Chromosomes
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4946898/
https://ncbi.nlm.nih.gov/pubmed/27228154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.12765
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