Thymoquinone subdues tumor growth and potentiates the chemopreventive effect of 5-fluorouracil on the early stages of colorectal carcinogenesis in rats

Colorectal cancer (CRC) is one of the most prevalent cancers and has a high mortality rate. Insensitivity and the limited therapeutic efficacy of its standard chemotherapeutic drug, 5-fluorouracil (5-FU), represents an important challenge in CRC treatment. The robust antitumor properties of thymoqui...

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Detalhes bibliográficos
Publicado no:Drug Des Devel Ther
Main Authors: Kensara, Osama Adnan, El-Shemi, Adel Galal, Mohamed, Amr Mohamed, Refaat, Bassem, Idris, Shakir, Ahmad, Jawwad
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2016
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4946859/
https://ncbi.nlm.nih.gov/pubmed/27468227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S109721
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