Vitamin D3 enhances the tumouricidal effects of 5-Fluorouracil through multipathway mechanisms in azoxymethane rat model of colon cancer

BACKGROUND: Vitamin D3 and its analogues have recently been shown to enhance the anti-tumour effects of 5- Fluorouracil (5-FU) both in vitro and in xenograft mouse model of colon cancer. This study measured the potential mechanism(s) by which vitamin D3 could synergise the tumouricidal activities of...

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Detalhes bibliográficos
Publicado no:J Exp Clin Cancer Res
Main Authors: Refaat, Bassem, El-Shemi, Adel Galal, Kensara, Osama Adnan, Mohamed, Amr Mohamed, Idris, Shakir, Ahmad, Jawwad, Khojah, Athar
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4513788/
https://ncbi.nlm.nih.gov/pubmed/26205949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-015-0187-9
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