Effect of the long-acting insulin analogues glargine and degludec on cardiomyocyte cell signalling and function

BACKGROUND: The effects of insulin on cardiomyocytes, such as positive inotropic action and glucose uptake are well described. However, in vitro studies comparing long-acting insulin analogues with regard to cardiomyocyte signalling and function have not been systematically conducted. METHODS: Insul...

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Detalles Bibliográficos
Publicado en:Cardiovasc Diabetol
Autores principales: Hartmann, Thorsten, Overhagen, Sabrina, Ouwens, D. Margriet, Raschke, Silja, Wohlfart, Paulus, Tennagels, Norbert, Wronkowitz, Nina, Eckel, Jürgen
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2016
Materias:
Original Investigation
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4946153/
https://ncbi.nlm.nih.gov/pubmed/27422524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12933-016-0410-9
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