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Metabolic effect and receptor signalling profile of a non-metabolisable insulin glargine analogue
CONTEXT: Insulin glargine (GLA) is rapidly metabolized in vivo to metabolite M1, which has in vitro metabolic and mitogenic profiles comparable with human insulin (HI). OBJECTIVE: To investigate the pharmacologic and signalling profiles of a non-metabolizable analogue (A21Gly,DiD-Arg) insulin (D-GLA...
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| Publié dans: | Arch Physiol Biochem |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Informa UK Ltd.
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4219851/ https://ncbi.nlm.nih.gov/pubmed/25144413 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/13813455.2014.950589 |
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