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Indole-3-carbinol protects against cisplatin-induced acute nephrotoxicity: role of calcitonin gene-related peptide and insulin-like growth factor-1

Nephrotoxicity associated with the clinical use of the anticancer drug cisplatin is a limiting problem. Thus, searching for new protective measures is required. Indole-3-carbinol is a powerful anti-oxidant, anti-inflammatory and anti-tumor agent. The present study aimed to investigate the potential...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: El-Naga, Reem N., Mahran, Yasmen F.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4945906/
https://ncbi.nlm.nih.gov/pubmed/27417335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep29857
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