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Indole-3- carbinol enhances sorafenib cytotoxicity in hepatocellular carcinoma cells: A mechanistic study

Sorafenib is the only chemotherapeutic agent currently approved for unresectable hepatocellular carcinoma (HCC). However, poor response rates have been widely reported. Indole-3-carbinol (I3C) is a potential chemopreventive phytochemical. The present study aimed to explore the potential chemomodulat...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Abdelmageed, Mai M., El-Naga, Reem N., El-Demerdash, Ebtehal, Elmazar, Mohamed M.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5017213/
https://ncbi.nlm.nih.gov/pubmed/27612096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep32733
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