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Key role of heat shock protein 90 in leptin‐induced STAT3 activation and feeding regulation

BACKGROUND AND PURPOSE: Leptin, an important regulator of the energy balance, acts on the brain to inhibit feeding. However, the mechanisms involved in leptin signalling have not yet been fully elucidated. Heat shock protein 90 (HSP90) is a molecular chaperone that is involved in regulating cellular...

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Publicat a:Br J Pharmacol
Autors principals: Hosoi, Toru, Kohda, Toshiko, Matsuzaki, Syu, Ishiguchi, Mizuho, Kuwamura, Ayaka, Akita, Tomoyuki, Tanaka, Junko, Ozawa, Koichiro
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4945768/
https://ncbi.nlm.nih.gov/pubmed/27205876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13520
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