Palmitic Acid and DGAT1 Deficiency Enhance Osteoclastogenesis, while Oleic Acid-Induced Triglyceride Formation Prevents It

Both obesity and diabetes mellitus are associated with alterations in lipid metabolism as well as a change in bone homeostasis and osteoclastogenesis. We hypothesized that increased fatty acid levels affect bone health by altering precursor cell differentiation and osteoclast activation. Here we sho...

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Bibliographic Details
Published in:J Bone Miner Res
Main Authors: Drosatos-Tampakaki, Zoi, Drosatos, Konstantinos, Siegelin, Yasemin, Gong, Shan, Khan, Salmiyeh, Van Dyke, Thomas, Goldberg, Ira J, Schulze, P Christian, Schulze-Späte, Ulrike
Format: Artigo
Language:Inglês
Published: 2014
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4945760/
https://ncbi.nlm.nih.gov/pubmed/24272998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.2150
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