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Aldosterone alters the chromatin structure of the murine endothelin-1 gene
Aldosterone increases sodium reabsorption in the renal collecting duct and systemic blood pressure. Paradoxically, aldosterone also induces transcription of the endothelin-1 (Edn1) gene to increase protein (ET-1) levels, which inhibits sodium reabsorption. AIMS: Here we investigated changes in the c...
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| 發表在: | Life Sci |
|---|---|
| Main Authors: | , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2016
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4945465/ https://ncbi.nlm.nih.gov/pubmed/26775567 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.lfs.2016.01.019 |
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