Higher-order oligomerization of Spc110p drives γ-tubulin ring complex assembly

The microtubule (MT) cytoskeleton plays important roles in many cellular processes. In vivo, MT nucleation is controlled by the γ-tubulin ring complex (γTuRC), a 2.1-MDa complex composed of γ-tubulin small complex (γTuSC) subunits. The mechanisms underlying the assembly of γTuRC are largely unknown....

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Publicat a:Mol Biol Cell
Autors principals: Lyon, Andrew S., Morin, Geneviève, Moritz, Michelle, Yabut, King Clyde B., Vojnar, Tamira, Zelter, Alex, Muller, Eric, Davis, Trisha N., Agard, David A.
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Cell Biology 2016
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4945142/
https://ncbi.nlm.nih.gov/pubmed/27226487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E16-02-0072
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