Multiplex Detection of Rare Mutations by Picoliter Droplet Based Digital PCR: Sensitivity and Specificity Considerations

In cancer research, the accuracy of the technology used for biomarkers detection is remarkably important. In this context, digital PCR represents a highly sensitive and reproducible method that could serve as an appropriate tool for tumor mutational status analysis. In particular, droplet-based digi...

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Veröffentlicht in:PLoS One
Hauptverfasser: Zonta, Eleonora, Garlan, Fanny, Pécuchet, Nicolas, Perez-Toralla, Karla, Caen, Ouriel, Milbury, Coren, Didelot, Audrey, Fabre, Elizabeth, Blons, Hélène, Laurent-Puig, Pierre, Taly, Valérie
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2016
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4945036/
https://ncbi.nlm.nih.gov/pubmed/27416070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0159094
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