Fluorinated Cannabidiol Derivatives: Enhancement of Activity in Mice Models Predictive of Anxiolytic, Antidepressant and Antipsychotic Effects

Cannabidiol (CBD) is a major Cannabis sativa constituent, which does not cause the typical marijuana psychoactivity. However, it has been shown to be active in a numerous pharmacological assays, including mice tests for anxiety, obsessive-compulsive disorder, depression and schizophrenia. In human t...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Breuer, Aviva, Haj, Christeene G., Fogaça, Manoela V., Gomes, Felipe V., Silva, Nicole Rodrigues, Pedrazzi, João Francisco, Del Bel, Elaine A., Hallak, Jaime C., Crippa, José A., Zuardi, Antonio W., Mechoulam, Raphael, Guimarães, Francisco S.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4945002/
https://ncbi.nlm.nih.gov/pubmed/27416026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0158779
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