Cannabidiol presents an inverted U-shaped dose-response curve in a simulated public speaking test

OBJECTIVE: Cannabidiol (CBD), one of the non-psychotomimetic compounds of Cannabis sativa, causes anxiolytic-like effects in animals, with typical bell-shaped dose-response curves. No study, however, has investigated whether increasing doses of this drug would also cause similar curves in humans. Th...

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Vydáno v:Braz J Psychiatry
Hlavní autoři: Linares, Ila M., Zuardi, Antonio W., Pereira, Luis C., Queiroz, Regina H., Mechoulam, Raphael, Guimarães, Francisco S., Crippa, José A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Associação Brasileira de Psiquiatria 2018
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6781714/
https://ncbi.nlm.nih.gov/pubmed/30328956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1590/1516-4446-2017-0015
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