Shear-Induced Nitric Oxide Production by Endothelial Cells

We present a biochemical model of the wall shear stress-induced activation of endothelial nitric oxide synthase (eNOS) in an endothelial cell. The model includes three key mechanotransducers: mechanosensing ion channels, integrins, and G protein-coupled receptors. The reaction cascade consists of tw...

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Bibliografische gegevens
Gepubliceerd in:Biophys J
Hoofdauteurs: Sriram, Krishna, Laughlin, Justin G., Rangamani, Padmini, Tartakovsky, Daniel M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Biophysical Society 2016
Onderwerpen:
Cell Biophysics
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4944664/
https://ncbi.nlm.nih.gov/pubmed/27410748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2016.05.034
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