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In Silico Modeling of Shear-Stress-Induced Nitric Oxide Production in Endothelial Cells through Systems Biology

Nitric oxide (NO) produced by vascular endothelial cells is a potent vasodilator and an antiinflammatory mediator. Regulating production of endothelial-derived NO is a complex undertaking, involving multiple signaling and genetic pathways that are activated by diverse humoral and biomechanical stimu...

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Détails bibliographiques
Auteurs principaux: Koo, Andrew, Nordsletten, David, Umeton, Renato, Yankama, Beracah, Ayyadurai, Shiva, García-Cardeña, Guillermo, Dewey, C. Forbes
Format: Artigo
Langue:Inglês
Publié: The Biophysical Society 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3660651/
https://ncbi.nlm.nih.gov/pubmed/23708369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.03.052
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