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Protein Composition Determines the Effect of Crowding on the Properties of Disordered Proteins

Unlike dilute experimental conditions under which biological molecules are typically characterized, the cell interior is crowded by macromolecules, which affects both the thermodynamics and kinetics of in vivo processes. Although the excluded-volume effects of macromolecular crowding are expected to...

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Pubblicato in:Biophys J
Autori principali: Miller, Cayla M., Kim, Young C., Mittal, Jeetain
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Biophysical Society 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4944663/
https://ncbi.nlm.nih.gov/pubmed/27410731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2016.05.033
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