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The Water Permeability and Pore Entrance Structure of Aquaporin-4 Depend on Lipid Bilayer Thickness

Aquaporin-4 (AQP4), the primary water channel in glial cells of the mammalian brain, plays a critical role in water transport in the central nervous system. Previous experiments have shown that the water permeability of AQP4 depends on the cholesterol content in the lipid bilayer, but it was not cle...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Tong, Jihong, Wu, Zhe, Briggs, Margaret M., Schulten, Klaus, McIntosh, Thomas J.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4944661/
https://ncbi.nlm.nih.gov/pubmed/27410737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2016.05.039
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