Water Permeability of Aquaporin-4 Channel Depends on Bilayer Composition, Thickness, and Elasticity

Aquaporin-4 (AQP4) is the primary water channel in the mammalian brain, particularly abundant in astrocytes, whose plasma membranes normally contain high concentrations of cholesterol. Here we test the hypothesis that the water permeabilities of two naturally occurring isoforms (AQP4-M1 and AQP4-M23...

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Hlavní autoři: Tong, Jihong, Briggs, Margaret M., McIntosh, Thomas J.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Biophysical Society 2012
Témata:
Membrane
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3491688/
https://ncbi.nlm.nih.gov/pubmed/23199918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.09.025
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