Bile Acids Act as Soluble Host Restriction Factors Limiting Cytomegalovirus Replication in Hepatocytes

The liver constitutes a prime site of cytomegalovirus (CMV) replication and latency. Hepatocytes produce, secrete, and recycle a chemically diverse set of bile acids, with the result that interactions between bile acids and cytomegalovirus inevitably occur. Here we determined the impact of naturally...

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Bibliographische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Schupp, Anna-Kathrin, Trilling, Mirko, Rattay, Stephanie, Le-Trilling, Vu Thuy Khanh, Haselow, Katrin, Stindt, Jan, Zimmermann, Albert, Häussinger, Dieter, Hengel, Hartmut, Graf, Dirk
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2016
Schlagworte:
Virus-Cell Interactions
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4944301/
https://ncbi.nlm.nih.gov/pubmed/27170759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00299-16
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