HIV-1-Specific Chimeric Antigen Receptors Based on Broadly Neutralizing Antibodies

Although the use of chimeric antigen receptors (CARs) based on single-chain antibodies for gene immunotherapy of cancers is increasing due to promising recent results, the earliest CAR therapeutic trials were done for HIV-1 infection in the late 1990s. This approach utilized a CAR based on human CD4...

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Bibliographic Details
Published in:J Virol
Main Authors: Ali, Ayub, Kitchen, Scott G., Chen, Irvin S. Y., Ng, Hwee L., Zack, Jerome A., Yang, Otto O.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2016
Subjects:
Pathogenesis and Immunity
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4944295/
https://ncbi.nlm.nih.gov/pubmed/27226366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00805-16
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