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Capsid-CPSF6 Interaction Is Dispensable for HIV-1 Replication in Primary Cells but Is Selected during Virus Passage In Vivo
Cleavage and polyadenylation specificity factor subunit 6 (CPSF6), a host factor that interacts with the HIV-1 capsid (CA) protein, is implicated in diverse functions during the early part of the HIV-1 life cycle, including uncoating, nuclear entry, and integration targeting. Preservation of CA bind...
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Опубликовано в: : | J Virol |
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Главные авторы: | , , , , , , , , , , , , , , |
Формат: | Artigo |
Язык: | Inglês |
Опубликовано: |
American Society for Microbiology
2016
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Предметы: | |
Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4944271/ https://ncbi.nlm.nih.gov/pubmed/27307565 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00019-16 |
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