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Capsid-CPSF6 Interaction Is Dispensable for HIV-1 Replication in Primary Cells but Is Selected during Virus Passage In Vivo

Cleavage and polyadenylation specificity factor subunit 6 (CPSF6), a host factor that interacts with the HIV-1 capsid (CA) protein, is implicated in diverse functions during the early part of the HIV-1 life cycle, including uncoating, nuclear entry, and integration targeting. Preservation of CA bind...

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Библиографические подробности
Опубликовано в: :J Virol
Главные авторы: Saito, Akatsuki, Henning, Matthew S., Serrao, Erik, Dubose, Brittany N., Teng, Samantha, Huang, Jing, Li, Xiangming, Saito, Namiko, Roy, Saumendra Prasad, Siddiqui, Mohammad Adnan, Ahn, Jinwoo, Tsuji, Moriya, Hatziioannou, Theodora, Engelman, Alan N., Yamashita, Masahiro
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2016
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4944271/
https://ncbi.nlm.nih.gov/pubmed/27307565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00019-16
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