Capsid-CPSF6 Interaction Is Dispensable for HIV-1 Replication in Primary Cells but Is Selected during Virus Passage In Vivo

Cleavage and polyadenylation specificity factor subunit 6 (CPSF6), a host factor that interacts with the HIV-1 capsid (CA) protein, is implicated in diverse functions during the early part of the HIV-1 life cycle, including uncoating, nuclear entry, and integration targeting. Preservation of CA bind...

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Dettagli Bibliografici
Pubblicato in:J Virol
Autori principali: Saito, Akatsuki, Henning, Matthew S., Serrao, Erik, Dubose, Brittany N., Teng, Samantha, Huang, Jing, Li, Xiangming, Saito, Namiko, Roy, Saumendra Prasad, Siddiqui, Mohammad Adnan, Ahn, Jinwoo, Tsuji, Moriya, Hatziioannou, Theodora, Engelman, Alan N., Yamashita, Masahiro
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2016
Soggetti:
Virus-Cell Interactions
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4944271/
https://ncbi.nlm.nih.gov/pubmed/27307565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00019-16
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