Activity of 2-Aryl-2-(3-indolyl)acetohydroxamates Against Drug-Resistant Cancer Cells

Many types of tumor, including glioma, melanoma, non-small cell lung, esophageal, head and neck cancer, among others, are intrinsically resistant to apoptosis induction and poorly responsive to current therapies with proapoptotic agents. In addition, tumors often develop multi-drug resistance based...

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Publicado en:J Med Chem
Autores principales: Aksenov, Alexander V., Smirnov, Alexander N., Magedov, Igor V., Reisenauer, Mary R., Aksenov, Nicolai A., Aksenova, Inna V., Pendleton, Alexander L., Nguyen, Gina, Johnston, Robert K., Rubin, Michael, De Carvalho, Annelise, Kiss, Robert, Mathieu, Véronique, Lefranc, Florence, Correa, Jaime, Cavazos, David A., Brenner, Andrew J., Bryan, Brad A., Rogelj, Snezna, Kornienko, Alexander, Frolova, Liliya V.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4944210/
https://ncbi.nlm.nih.gov/pubmed/25671501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm501518y
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