Population Pharmacokinetic Modeling of Cefadroxil Renal Transport in Wildtype and Pept2 Knockout Mice

1. Cefadroxil is a broad-spectrum β-lactam antibiotic that is widely used in the treatment of various infectious diseases. Currently, poor understanding of the drug’s pharmacokinetic profiles and disposition mechanism(s) prevents determining optimal dosage regimens and achieving ideal antibacterial...

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Bibliographic Details
Published in:Xenobiotica
Main Authors: Xie, Yehua, Shen, Hong, Hu, Yongjun, Feng, Meihua Rose, Smith, David E.
Format: Artigo
Language:Inglês
Published: 2015
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4944204/
https://ncbi.nlm.nih.gov/pubmed/26372256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/00498254.2015.1080881
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