New paradigms for understanding and step changes in treating active and chronic, persistent apicomplexan infections

Toxoplasma gondii, the most common parasitic infection of human brain and eye, persists across lifetimes, can progressively damage sight, and is currently incurable. New, curative medicines are needed urgently. Herein, we develop novel models to facilitate drug development: EGS strain T. gondii form...

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Udgivet i:Sci Rep
Main Authors: McPhillie, Martin, Zhou, Ying, El Bissati, Kamal, Dubey, Jitender, Lorenzi, Hernan, Capper, Michael, Lukens, Amanda K, Hickman, Mark, Muench, Stephen, Verma, Shiv Kumar, Weber, Christopher R., Wheeler, Kelsey, Gordon, James, Sanders, Justin, Moulton, Hong, Wang, Kai, Kim, Taek-Kyun, He, Yuqing, Santos, Tatiana, Woods, Stuart, Lee, Patty, Donkin, David, Kim, Eric, Fraczek, Laura, Lykins, Joseph, Esaa, Farida, Alibana-Clouser, Fatima, Dovgin, Sarah, Weiss, Louis, Brasseur, Gael, Wirth, Dyann, Kent, Michael, Hood, Leroy, Meunieur, Brigitte, Roberts, Craig W., Hasnain, S. Samar, Antonyuk, Svetlana V., Fishwick, Colin, McLeod, Rima
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4944145/
https://ncbi.nlm.nih.gov/pubmed/27412848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep29179
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