Beta-amyloid precursor protein cleavage by a membrane-bound protease.
The principal component of amyloid plaques in Alzheimer disease is beta-amyloid protein, an approximately 4-kDa peptide derived from amyloid precursor proteins. Previous studies have established that amyloid precursor proteins are secreted after proteolytic cleavage within the beta-amyloid peptide....
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1992
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC49440/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1631093/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.13.6075 |
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