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Structural study of the G57W mutant of human gamma-S-crystallin, associated with congenital cataract

PURPOSE: Human γS-crystallin (CrygS) is an important component of the human eye lens nucleus and cortex. The mutation G57W in the molecule is reported to be associated with congenital cataract in children. We compare the conformational features and aggregation properties of the mutant protein G57W w...

詳細記述

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書誌詳細
出版年:Mol Vis
主要な著者: Khan, Ismail, Chandani, Sushil, Balasubramanian, Dorairajan
フォーマット: Artigo
言語:Inglês
出版事項: Molecular Vision 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4943855/
https://ncbi.nlm.nih.gov/pubmed/27440995
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