Is copper hepatotoxic in primary biliary cirrhosis?

In primary biliary cirrhosis (PBC) liver copper retention occurs as a complication of cholestasis. By analogy with Wilson's disease, it has been suggested that copper retention is hepatotoxic in PBC, and this has been the rationale for the use of D-penicillamine in this disease. The hypothesis that...

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Detalles Bibliográficos

Publicado en:	J Clin Pathol
Principais autores:	Epstein, O, Arborgh, B, Sagiv, M, Wroblewski, R, Scheuer, P J, Sherlock, S
Formato:	Artigo
Idioma:	Inglês
Publicado:	BMJ Publishing Group 1981
Assuntos:	Research Article
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC494366/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7309888/ https://ncbi.nlm.nih.govhttps://doi.org/10.1136/jcp.34.10.1071
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