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Is copper hepatotoxic in primary biliary cirrhosis?

In primary biliary cirrhosis (PBC) liver copper retention occurs as a complication of cholestasis. By analogy with Wilson's disease, it has been suggested that copper retention is hepatotoxic in PBC, and this has been the rationale for the use of D-penicillamine in this disease. The hypothesis...

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Detalles Bibliográficos
Main Authors: Epstein, O, Arborgh, B, Sagiv, M, Wroblewski, R, Scheuer, P J, Sherlock, S
Formato: Artigo
Idioma:Inglês
Publicado: 1981
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC494366/
https://ncbi.nlm.nih.gov/pubmed/7309888
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