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Is copper hepatotoxic in primary biliary cirrhosis?

In primary biliary cirrhosis (PBC) liver copper retention occurs as a complication of cholestasis. By analogy with Wilson's disease, it has been suggested that copper retention is hepatotoxic in PBC, and this has been the rationale for the use of D-penicillamine in this disease. The hypothesis...

詳細記述

保存先:
書誌詳細
主要な著者: Epstein, O, Arborgh, B, Sagiv, M, Wroblewski, R, Scheuer, P J, Sherlock, S
フォーマット: Artigo
言語:Inglês
出版事項: 1981
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC494366/
https://ncbi.nlm.nih.gov/pubmed/7309888
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