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Sphaeropsidin A shows promising activity against drug-resistant cancer cells by targeting regulatory volume increase

Despite the recent advances in the treatment of tumors with intrinsic chemotherapy resistance, such as melanoma and renal cancers, their prognosis remains poor and new chemical agents with promising activity against these cancers are urgently needed. Sphaeropsidin A, a fungal metabolite whose antica...

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Détails bibliographiques
Publié dans:Cell Mol Life Sci
Auteurs principaux: Mathieu, Véronique, Chantôme, Aurélie, Lefranc, Florence, Cimmino, Alessio, Miklos, Walter, Paulitschke, Verena, Mohr, Thomas, Maddau, Lucia, Kornienko, Alexander, Berger, Walter, Vandier, Christophe, Evidente, Antonio, Delpire, Eric, Kiss, Robert
Format: Artigo
Langue:Inglês
Publié: Springer Basel 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4943577/
https://ncbi.nlm.nih.gov/pubmed/25868554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-015-1902-6
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