Deciphering the chemical instability of sphaeropsidin A under physiological conditions – degradation studies and structural elucidation of the major metabolite

The fungal metabolite sphaeropsidin A (SphA) has been recognised for its promising cytotoxicity, particularly towards apoptosis- and multidrug-resistant cancers. Owing to its intriguing activity, the development of SphA as a potential anticancer agent has been pursued. However, this endeavour is com...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Org Biomol Chem
Main Authors: van der Westhuyzen, Alet E., Ingels, Aude, Rosière, Rémi, Amighi, Karim, Oberer, Lukas, Gustafson, Kirk R., Wang, Dongdong, Evidente, Antonio, Maddau, Lucia, Masi, Marco, de Villiers, André, Green, Ivan R., Berger, Walter, Kornienko, Alexander, Mathieu, Veronique, van Otterlo, Willem A. L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7881364/
https://ncbi.nlm.nih.gov/pubmed/33016969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0ob01586e
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados