Plasma Phospholipid and Sphingolipid Alterations in Presenilin1 Mutation Carriers: A Pilot Study

BACKGROUND AND OBJECTIVE: Aberrant lipid metabolism has been implicated in sporadic Alzheimer’s disease (AD). The current study investigated plasma phospholipid and sphingolipid profiles in individuals carrying PSEN1 mutations responsible for autosomal dominant AD (ADAD). METHODS: Study participants...

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Detalhes bibliográficos
Publicado no:J Alzheimers Dis
Main Authors: Chatterjee, Pratishtha, Lim, Wei L.F., Shui, Guanghou, Gupta, Veer B., James, Ian, Fagan, Anne M., Xiong, Chengjie, Sohrabi, Hamid R., Taddei, Kevin, Brown, Belinda M., Benzinger, Tammie, Masters, Colin, Snowden, Stuart G., Wenk, Marcus R., Bateman, Randall J., Morris, John C., Martins, Ralph N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4943576/
https://ncbi.nlm.nih.gov/pubmed/26836186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-150948
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