A flexible, multilayered protein scaffold maintains the slit in between glomerular podocytes

Vertebrate life critically depends on renal filtration and excretion of low molecular weight waste products. This process is controlled by a specialized cell-cell contact between podocyte foot processes: the slit diaphragm (SD). Using a comprehensive set of targeted KO mice of key SD molecules, we p...

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Détails bibliographiques
Publié dans:JCI Insight
Auteurs principaux: Grahammer, Florian, Wigge, Christoph, Schell, Christoph, Kretz, Oliver, Patrakka, Jaakko, Schneider, Simon, Klose, Martin, Kind, Julia, Arnold, Sebastian J., Habermann, Anja, Bräuniger, Ricarda, Rinschen, Markus M., Völker, Linus, Bregenzer, Andreas, Rubbenstroth, Dennis, Boerries, Melanie, Kerjaschki, Dontscho, Miner, Jeffrey H., Walz, Gerd, Benzing, Thomas, Fornoni, Alessia, Frangakis, Achilleas S., Huber, Tobias B.
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 2016
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4943462/
https://ncbi.nlm.nih.gov/pubmed/27430022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.86177
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