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Nephrin Localizes at the Podocyte Filtration Slit Area and Is Characteristically Spliced in the Human Kidney

Defects in the newly reported gene NPHS1 in chromosome 19 cause the massive proteinuria of Finnish type congenital nephrotic syndrome (CNF). Together with its gene product, nephrin, NPHS1 is providing new understanding of the pathophysiological mechanisms of glomerular filtration. Here we show the c...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Holthöfer, Harry, Ahola, Heikki, Solin, Marja-Liisa, Wang, Shixuan, Palmen, Tuula, Luimula, Pauliina, Miettinen, Aaro, Kerjaschki, Dontscho
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Investigative Pathology 1999
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1866978/
https://ncbi.nlm.nih.gov/pubmed/10550324
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