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Cancer Incidence in First- and Second-Degree Relatives of BRCA1 and BRCA2 Mutation Carriers

BACKGROUND. Mutations in the BRCA1 and BRCA2 genes are associated with increased risk of breast, ovarian, and several other cancers. The purpose of the present study was to evaluate the incidence of cancer in first- and second-degree relatives of BRCA mutation carriers compared with the general popu...

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Опубликовано в: :Oncologist
Главные авторы: Streff, Haley, Profato, Jessica, Ye, Yuanqing, Nebgen, Denise, Peterson, Susan K., Singletary, Claire, Arun, Banu K., Litton, Jennifer K.
Формат: Artigo
Язык:Inglês
Опубликовано: AlphaMed Press 2016
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4943383/
https://ncbi.nlm.nih.gov/pubmed/27306910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2015-0354
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