High Incidence of Germline BRCA Mutation in Patients with ER low positive/PR low positive/HER-2 neu negative Tumors

PURPOSE: 2015 NCCN guidelines recommend genetic counseling and germline BRCA mutation testing be offered to women under age 60 with triple negative breast cancer (TNBC). As a result of the 2010 ASCO/CAP guidelines in breast cancer, patients with breast cancers that are ER or PR low-positive (1–9% on...

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Publicado en:Cancer
Main Authors: Sanford, Rachel Ann, Song, Juhee, Gutierrez-Barrera, Angelica M., Profato, Jessica, Woodson, Ashley, Litton, Jennifer Keating, Bedrosian, Isabelle, Albarracin, Constance T., Valero, Vicente, Arun, Banu
Formato: Artigo
Idioma:Inglês
Publicado: 2015
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4829956/
https://ncbi.nlm.nih.gov/pubmed/26280679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.29572
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