Alterations in Multi‐Scale Cardiac Architecture in Association With Phosphorylation of Myosin Binding Protein‐C

BACKGROUND: The geometric organization of myocytes in the ventricular wall comprises the structural underpinnings of cardiac mechanical function. Cardiac myosin binding protein‐C (MYBPC3) is a sarcomeric protein, for which phosphorylation modulates myofilament binding, sarcomere morphology, and myoc...

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Veröffentlicht in:J Am Heart Assoc
Hauptverfasser: Taylor, Erik N., Hoffman, Matthew P., Barefield, David Y., Aninwene, George E., Abrishamchi, Aurash D., Lynch, Thomas L., Govindan, Suresh, Osinska, Hanna, Robbins, Jeffrey, Sadayappan, Sakthivel, Gilbert, Richard J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2016
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Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4943261/
https://ncbi.nlm.nih.gov/pubmed/27068630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.115.002836
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