Sample Size in Clinical Cardioprotection Trials Using Myocardial Salvage Index, Infarct Size, or Biochemical Markers as Endpoint

BACKGROUND: Cardiac magnetic resonance (CMR) can quantify myocardial infarct (MI) size and myocardium at risk (MaR), enabling assessment of myocardial salvage index (MSI). We assessed how MSI impacts the number of patients needed to reach statistical power in relation to MI size alone and levels of...

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Dades bibliogràfiques
Publicat a:J Am Heart Assoc
Autors principals: Engblom, Henrik, Heiberg, Einar, Erlinge, David, Jensen, Svend Eggert, Nordrehaug, Jan Erik, Dubois‐Randé, Jean‐Luc, Halvorsen, Sigrun, Hoffmann, Pavel, Koul, Sasha, Carlsson, Marcus, Atar, Dan, Arheden, Håkan
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2016
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4943247/
https://ncbi.nlm.nih.gov/pubmed/26961520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.115.002708
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