Sample Size in Clinical Cardioprotection Trials Using Myocardial Salvage Index, Infarct Size, or Biochemical Markers as Endpoint

BACKGROUND: Cardiac magnetic resonance (CMR) can quantify myocardial infarct (MI) size and myocardium at risk (MaR), enabling assessment of myocardial salvage index (MSI). We assessed how MSI impacts the number of patients needed to reach statistical power in relation to MI size alone and levels of...

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Detalhes bibliográficos
Publicado no:J Am Heart Assoc
Main Authors: Engblom, Henrik, Heiberg, Einar, Erlinge, David, Jensen, Svend Eggert, Nordrehaug, Jan Erik, Dubois‐Randé, Jean‐Luc, Halvorsen, Sigrun, Hoffmann, Pavel, Koul, Sasha, Carlsson, Marcus, Atar, Dan, Arheden, Håkan
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4943247/
https://ncbi.nlm.nih.gov/pubmed/26961520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.115.002708
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