Sample Size in Clinical Cardioprotection Trials Using Myocardial Salvage Index, Infarct Size, or Biochemical Markers as Endpoint

BACKGROUND: Cardiac magnetic resonance (CMR) can quantify myocardial infarct (MI) size and myocardium at risk (MaR), enabling assessment of myocardial salvage index (MSI). We assessed how MSI impacts the number of patients needed to reach statistical power in relation to MI size alone and levels of...

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Dettagli Bibliografici
Pubblicato in:J Am Heart Assoc
Autori principali: Engblom, Henrik, Heiberg, Einar, Erlinge, David, Jensen, Svend Eggert, Nordrehaug, Jan Erik, Dubois‐Randé, Jean‐Luc, Halvorsen, Sigrun, Hoffmann, Pavel, Koul, Sasha, Carlsson, Marcus, Atar, Dan, Arheden, Håkan
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2016
Soggetti:
Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4943247/
https://ncbi.nlm.nih.gov/pubmed/26961520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.115.002708
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