Sample Size in Clinical Cardioprotection Trials Using Myocardial Salvage Index, Infarct Size, or Biochemical Markers as Endpoint

BACKGROUND: Cardiac magnetic resonance (CMR) can quantify myocardial infarct (MI) size and myocardium at risk (MaR), enabling assessment of myocardial salvage index (MSI). We assessed how MSI impacts the number of patients needed to reach statistical power in relation to MI size alone and levels of...

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Bibliographic Details
Published in:J Am Heart Assoc
Main Authors: Engblom, Henrik, Heiberg, Einar, Erlinge, David, Jensen, Svend Eggert, Nordrehaug, Jan Erik, Dubois‐Randé, Jean‐Luc, Halvorsen, Sigrun, Hoffmann, Pavel, Koul, Sasha, Carlsson, Marcus, Atar, Dan, Arheden, Håkan
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2016
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Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4943247/
https://ncbi.nlm.nih.gov/pubmed/26961520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.115.002708
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