Hematopoietic Stem Cells from Ts65Dn Mice Are Deficient in the Repair of DNA Double-Strand Breaks

Down syndrome (DS) is a genetic disorder caused by the presence of an extra partial or whole copy of chromosome 21. In addition to musculoskeletal and neurodevelopmental abnormalities, children with DS exhibit various hematologic disorders and have an increased risk of developing acute lymphoblastic...

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Veröffentlicht in:Radiat Res
Hauptverfasser: Wang, Yingying, Chang, Jianhui, Shao, Lijian, Feng, Wei, Luo, Yi, Chow, Marie, Du, Wei, Meng, Aimin, Zhou, Daohong
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4943077/
https://ncbi.nlm.nih.gov/pubmed/27243896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1667/RR14407.1
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