Hematopoietic Stem Cells from Ts65Dn Mice Are Deficient in the Repair of DNA Double-Strand Breaks

Down syndrome (DS) is a genetic disorder caused by the presence of an extra partial or whole copy of chromosome 21. In addition to musculoskeletal and neurodevelopmental abnormalities, children with DS exhibit various hematologic disorders and have an increased risk of developing acute lymphoblastic...

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Publicado en:Radiat Res
Autores principales: Wang, Yingying, Chang, Jianhui, Shao, Lijian, Feng, Wei, Luo, Yi, Chow, Marie, Du, Wei, Meng, Aimin, Zhou, Daohong
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4943077/
https://ncbi.nlm.nih.gov/pubmed/27243896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1667/RR14407.1
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