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Monoubiquitination of syntaxin 5 regulates Golgi membrane dynamics during the cell cycle
The Golgi apparatus undergoes a ubiquitin-dependent disassembly and reassembly process during each cycle of cell division. Here we report the identification of the Golgi t-SNARE syntaxin 5 (Syn5) as the ubiquitinated substrate. Syn5 is monoubiquitinated by the ubiquitin ligase HACE1 in early mitosis...
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| Veröffentlicht in: | Dev Cell |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4942811/ https://ncbi.nlm.nih.gov/pubmed/27404360 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2016.06.001 |
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