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Monoubiquitination of syntaxin 5 regulates Golgi membrane dynamics during the cell cycle

The Golgi apparatus undergoes a ubiquitin-dependent disassembly and reassembly process during each cycle of cell division. Here we report the identification of the Golgi t-SNARE syntaxin 5 (Syn5) as the ubiquitinated substrate. Syn5 is monoubiquitinated by the ubiquitin ligase HACE1 in early mitosis...

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Publicat a:Dev Cell
Autors principals: Huang, Shijiao, Tang, Danming, Wang, Yanzhuang
Format: Artigo
Idioma:Inglês
Publicat: 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4942811/
https://ncbi.nlm.nih.gov/pubmed/27404360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2016.06.001
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